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Depression subtype discovery gives hope to sufferers

Researchers at the University of Sydney have identified a new depression subtype linked to the body clock. Known as circadian depression, it was found in about a quarter of more than 10,000 Australians in a recent study. Lead researcher Ian Hickie said the finding could help people whose depression had not responded to traditional treatments. Treatments may involve monitoring and regulating sleep-wake cycles. A major trial of melatonin as a possible treatment is also under way, with results expected in a few years.

ABC News Politics· This weekHealth

One in four people with severe depression may have a dysregulated body clock

A new Australian study suggests about one in four people with severe, recurrent or persistent depression may have circadian depression, a proposed subtype linked to the body's internal clock. Researchers say people with it often describe themselves as night owls or wake up very tired. Lead researcher Emiliana Tonini said the findings could help give people earlier access to the treatments most likely to work for them. The study found these patients reported more severe symptoms and may have a different genetic profile. Experts say more research is needed before it could be used in clinical practice.

Guardian AU· This weekHealth

Australian researchers identify new subtype of depression linked to body clock disruptions

Australian researchers have identified a new subtype of depression, called circadian depression, linked to disruptions in the body's internal clock. The study, published in the British Journal of Psychiatry, found it affected about 23 per cent of 11,380 participants, mostly with severe and recurrent depression. Those with the subtype were less responsive to common antidepressants, so the researchers suggest treatments such as melatonin and light therapy may help. Lead author Dr Emiliana Tonini said the subtype appears to have a distinct biology, not simply poor sleep. Some outside experts described the findings as interesting but preliminary.

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#Circadian RhythmTopic

Depression subtype discovery gives hope to sufferers

One in four people with severe depression may have a dysregulated body clock

Australian researchers identify new subtype of depression linked to body clock disruptions

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Depression subtype discovery gives hope to sufferers

One in four people with severe depression may have a dysregulated body clock

Australian researchers identify new subtype of depression linked to body clock disruptions